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GWAS Study

Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.

Qi L, Qi Q, Prudente S et al.

23982368 PubMed ID
GWAS Study Type
4188 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

QL
Qi L
QQ
Qi Q
PS
Prudente S
MC
Mendonca C
AF
Andreozzi F
DP
di Pietro N
SM
Sturma M
NV
Novelli V
MG
Mannino GC
FG
Formoso G
GE
Gervino EV
HT
Hauser TH
MJ
Muehlschlegel JD
NM
Niewczas MA
KA
Krolewski AS
BG
Biolo G
PA
Pandolfi A
RE
Rimm E
SG
Sesti G
TV
Trischitta V
HF
Hu F
DA
Doria A
Chapter II

Abstract

Summary of the research findings

Importance: Diabetes is associated with an elevated risk of coronary heart disease (CHD). Previous studies have suggested that the genetic factors predisposing to excess cardiovascular risk may be different in diabetic and nondiabetic individuals.

669 European ancestry cases, 1,641 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

4188
Total Participants
GWAS
Study Type
Yes
Replicated
848 European ancestry cases, 1,030 European ancestry controls
Replication Participants
European
Ancestry
U.S., Italy
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.