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GWAS Study

Genome-wide association study identifies variants associated with autoimmune hepatitis type 1.

de Boer YS, van Gerven NM, Zwiers A et al.

24768677 PubMed ID
GWAS Study Type
18639 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DB
de Boer YS
VG
van Gerven NM
ZA
Zwiers A
VB
Verwer BJ
VH
van Hoek B
VE
van Erpecum KJ
BU
Beuers U
VB
van Buuren HR
DJ
Drenth JP
DO
den Ouden JW
VR
Verdonk RC
KG
Koek GH
BJ
Brouwer JT
GM
Guichelaar MM
VJ
Vrolijk JM
KG
Kraal G
MC
Mulder CJ
VN
van Nieuwkerk CM
FJ
Fischer J
BT
Berg T
SF
Stickel F
SC
Sarrazin C
SC
Schramm C
LA
Lohse AW
WC
Weiler-Normann C
LM
Lerch MM
NM
Nauck M
VH
Völzke H
HG
Homuth G
BE
Bloemena E
VH
Verspaget HW
KV
Kumar V
ZA
Zhernakova A
WC
Wijmenga C
FL
Franke L
BG
Bouma G
Chapter II

Abstract

Summary of the research findings

Background & aims: Autoimmune hepatitis (AIH) is an uncommon autoimmune liver disease of unknown etiology. We used a genome-wide approach to identify genetic variants that predispose individuals to AIH.

649 European ancestry cases, 13,436 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

18639
Total Participants
GWAS
Study Type
Yes
Replicated
451 European ancestry cases, 4,103 European ancestry controls
Replication Participants
European
Ancestry
Germany, Switzerland, Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.