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GWAS Study

No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk.

Du M, Zhang X, Hoffmeister M et al.

25192705 PubMed ID
GWAS Study Type
18509 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DM
Du M
ZX
Zhang X
HM
Hoffmeister M
SR
Schoen RE
BJ
Baron JA
BS
Berndt SI
BH
Brenner H
CC
Carlson CS
CG
Casey G
CA
Chan AT
CK
Curtis KR
DD
Duggan D
GW
Gauderman WJ
GE
Giovannucci EL
GJ
Gong J
HT
Harrison TA
HR
Hayes RB
HB
Henderson BE
HJ
Hopper JL
HL
Hsu L
HT
Hudson TJ
HC
Hutter CM
JM
Jenkins MA
JS
Jiao S
KJ
Kocarnik JM
KL
Kolonel LN
LM
Le Marchand L
LY
Lin Y
NP
Newcomb PA
RA
Rudolph A
SD
Seminara D
TM
Thornquist MD
UC
Ulrich CM
WE
White E
WK
Wu K
ZB
Zanke BW
CP
Campbell PT
SM
Slattery ML
PU
Peters U
CJ
Chang-Claude J
PJ
Potter JD
Chapter II

Abstract

Summary of the research findings

Calcium intake may reduce risk of colorectal cancer, but the mechanisms remain unclear. Studies of interaction between calcium intake and SNPs in calcium-related pathways have yielded inconsistent results.

9,006 European ancestry cases, 9,503 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

18509
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.