Immunochip analysis identification of 6 additional susceptibility loci for Crohn's disease in Koreans.
Yang SK, Hong M, Choi H et al.
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Abstract
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Crohn's disease (CD) is an intractable inflammatory bowel disease of unknown cause. Recent genome-wide association studies of CD in Korean and Japanese populations suggested marginal sharing of susceptibility loci between Caucasian and Asian populations. As the 7 identified loci altogether explain 5.31% of the risk for CD, the objective of this study was to identify additional CD susceptibility loci in the Korean population.
722 Korean ancestry cases, 461 Korean ancestry controls
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