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GWAS Study

Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study.

Yu H, Yan H, Wang L et al.

29503163 PubMed ID
GWAS Study Type
3792 Participants
38 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

YH
Yu H
YH
Yan H
WL
Wang L
LJ
Li J
TL
Tan L
DW
Deng W
CQ
Chen Q
YG
Yang G
ZF
Zhang F
LT
Lu T
YJ
Yang J
LK
Li K
LL
Lv L
TQ
Tan Q
ZH
Zhang H
XX
Xiao X
LM
Li M
MX
Ma X
YF
Yang F
LL
Li L
WC
Wang C
LT
Li T
ZD
Zhang D
YW
Yue W
Chapter II

Abstract

Summary of the research findings

Antipsychotic drugs improve schizophrenia symptoms and reduce the frequency of relapse, but treatment response is highly variable. Little is known about the genetic factors associated with treatment response. We did a genome-wide association study of antipsychotic treatment response in patients with schizophrenia.

2,413 Han Chinese ancestry cases

Chapter III

Study Statistics

Key metrics and study information

3792
Total Participants
GWAS
Study Type
Yes
Replicated
1,379 Han Chinese ancestry cases
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

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