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GWAS Study

Genome-wide association analysis suggests novel loci for Hashimoto's thyroiditis.

Brčić L, Barić A, Gračan S et al.

30284222 PubMed ID
GWAS Study Type
1443 Participants
212 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BL
Brčić L
BA
Barić A
GS
Gračan S
BM
Brekalo M
KD
Kaličanin D
GI
Gunjača I
TL
Torlak Lovrić V
TS
Tokić S
RM
Radman M
ŠV
Škrabić V
MA
Miljković A
KI
Kolčić I
ŠM
Štefanić M
GL
Glavaš-Obrovac L
LD
Lessel D
PO
Polašek O
ZT
Zemunik T
BM
Barbalić M
PA
Punda A
BP
Boraska Perica V
Chapter II

Abstract

Summary of the research findings

Purpose: Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid diseases. Current knowledge of HT genetics is limited, and not a single genome-wide association study (GWAS) focusing exclusively on HT has been performed to date. In order to decipher genetic determinants of HT, we performed the first GWAS followed by replication in a total of 1443 individuals from Croatia.

405 Croatian ancestry cases, 433 Croatian ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1443
Total Participants
GWAS
Study Type
Yes
Replicated
303 Croatian ancestry cases, 302 Croatian ancestry controls
Replication Participants
European
Ancestry
Croatia
Recruitment Country
Chapter IV

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