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GWAS Study

Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin.

Joseph CB, Mariniello M, Yoshifuji A et al.

35228297 PubMed ID
GWAS Study Type
29315 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JC
Joseph CB
MM
Mariniello M
YA
Yoshifuji A
SG
Schiano G
LJ
Lake J
MJ
Marten J
RA
Richmond A
HJ
Huffman JE
CA
Campbell A
HS
Harris SE
TS
Troyanov S
CM
Cocca M
RA
Robino A
TS
Thériault S
EK
Eckardt KU
WM
Wuttke M
CY
Cheng Y
CT
Corre T
KI
Kolcic I
BC
Black C
BV
Bruat V
CM
Concas MP
SC
Sala C
AS
Aeschbacher S
SF
Schaefer F
BS
Bergmann S
CH
Campbell H
OM
Olden M
PO
Polasek O
PD
Porteous DJ
DI
Deary IJ
MF
Madore F
AP
Awadalla P
GG
Girotto G
US
Ulivi S
CD
Conen D
WE
Wuehl E
OE
Olinger E
WJ
Wilson JF
BM
Bochud M
KA
Köttgen A
HC
Hayward C
DO
Devuyst O
Chapter II

Abstract

Summary of the research findings

Uromodulin, the most abundant protein excreted in normal urine, plays major roles in kidney physiology and disease. The mechanisms regulating the urinary excretion of uromodulin remain essentially unknown.

29,315 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

29315
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Canada, U.S., Liechtenstein, Italy, U.K., Switzerland, Germany, Croatia
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.