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GWAS Study

Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer.

Dong Q, Song N, Qin N et al.

35313970 PubMed ID
GWAS Study Type
2640 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DQ
Dong Q
SN
Song N
QN
Qin N
CC
Chen C
LZ
Li Z
SX
Sun X
EJ
Easton J
MH
Mulder H
PE
Plyler E
NG
Neale G
WE
Walker E
LQ
Li Q
MX
Ma X
CX
Chen X
HI
Huang IC
YY
Yasui Y
NK
Ness KK
ZJ
Zhang J
HM
Hudson MM
RL
Robison LL
WZ
Wang Z
Chapter II

Abstract

Summary of the research findings

Increased epigenetic age acceleration (EAA) in survivors of childhood cancer is associated with specific treatment exposures, unfavorable health behaviors, and presence of certain chronic health conditions. To better understand inter-individual variability, we investigated the genetic basis underlying EAA.

2,640 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

2640
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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