Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci.
Chen H, Fan S, Stone J et al.
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Abstract
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Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA), are associated with breast cancer risk. Twin studies suggest that MD phenotypes are highly heritable. However, only a small proportion of their variance is explained by identified genetic variants.
24,579 European ancestry females
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