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GWAS Study

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.

Morra A, Escala-Garcia M, Beesley J et al.

34407845 PubMed ID
GWAS Study Type
91686 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MA
Morra A
EM
Escala-Garcia M
BJ
Beesley J
KR
Keeman R
CS
Canisius S
AT
Ahearn TU
AI
Andrulis IL
AH
Anton-Culver H
AV
Arndt V
AP
Auer PL
AA
Augustinsson A
BF
Beane Freeman LE
BH
Becher H
BM
Beckmann MW
BS
Behrens S
BS
Bojesen SE
BM
Bolla MK
BH
Brenner H
BT
Brüning T
BS
Buys SS
CB
Caan B
CD
Campa D
CF
Canzian F
CJ
Castelao JE
CJ
Chang-Claude J
CS
Chanock SJ
CT
Cheng TD
CC
Clarke CL
CS
Colonna SV
CF
Couch FJ
CA
Cox A
CS
Cross SS
CK
Czene K
DM
Daly MB
DJ
Dennis J
DT
Dörk T
DL
Dossus L
DA
Dunning AM
DM
Dwek M
ED
Eccles DM
EA
Ekici AB
EA
Eliassen AH
EM
Eriksson M
ED
Evans DG
FP
Fasching PA
FH
Flyger H
FL
Fritschi L
GM
Gago-Dominguez M
GJ
García-Sáenz JA
GG
Giles GG
GM
Grip M
GP
Guénel P
GM
Gündert M
HE
Hahnen E
HC
Haiman CA
HN
Håkansson N
HP
Hall P
HU
Hamann U
HS
Hart SN
HJ
Hartikainen JM
HA
Hartmann A
HW
He W
HM
Hooning MJ
HR
Hoppe R
HJ
Hopper JL
HA
Howell A
HD
Hunter DJ
JA
Jager A
JA
Jakubowska A
JW
Janni W
JE
John EM
JA
Jung AY
KR
Kaaks R
KM
Keupers M
KC
Kitahara CM
KS
Koutros S
KP
Kraft P
KV
Kristensen VN
KA
Kurian AW
LJ
Lacey JV
LD
Lambrechts D
LM
Le Marchand L
LA
Lindblom A
LM
Linet M
LR
Luben RN
LJ
Lubiński J
LM
Lush M
MA
Mannermaa A
MM
Manoochehri M
MS
Margolin S
MJ
Martens JWM
MM
Martinez ME
MD
Mavroudis D
MK
Michailidou K
MR
Milne RL
MA
Mulligan AM
MT
Muranen TA
NH
Nevanlinna H
NW
Newman WG
NS
Nielsen SF
NB
Nordestgaard BG
OA
Olshan AF
OH
Olsson H
ON
Orr N
PT
Park-Simon TW
PA
Patel AV
PB
Peissel B
PP
Peterlongo P
PD
Plaseska-Karanfilska D
PK
Prajzendanc K
PR
Prentice R
PN
Presneau N
RB
Rack B
RG
Rennert G
RH
Rennert HS
RV
Rhenius V
RA
Romero A
RR
Roylance R
RM
Ruebner M
SE
Saloustros E
SE
Sawyer EJ
SR
Schmutzler RK
SA
Schneeweiss A
SC
Scott C
SM
Shah M
SS
Smichkoska S
SM
Southey MC
SJ
Stone J
SH
Surowy H
SA
Swerdlow AJ
TR
Tamimi RM
TW
Tapper WJ
TL
Teras LR
TM
Terry MB
TR
Tollenaar RAEM
TI
Tomlinson I
TM
Troester MA
TT
Truong T
VC
Vachon CM
WQ
Wang Q
HA
Hurson AN
WR
Winqvist R
WA
Wolk A
ZA
Ziogas A
BH
Brauch H
GM
García-Closas M
PP
Pharoah PDP
ED
Easton DF
CG
Chenevix-Trench G
SM
Schmidt MK
Chapter II

Abstract

Summary of the research findings

Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast cancer patients.

91,686 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

91686
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Republic of Ireland, Spain, Greece, New Zealand, The former Yugoslav Republic of Macedonia, Netherlands, Sweden, U.S., Belgium, Norway, Finland, Denmark, Poland, Italy, Israel, U.K., Australia, France, Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.