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Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.

Gumilang RA, Bai CH

41006820 PubMed ID
GWAS Study Type
49188 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GR
Gumilang RA
BC
Bai CH
Chapter II

Abstract

Summary of the research findings

Genetic predisposition to central adiposity is associated with metabolic dysfunction and obesity-related hypertension. This study investigated the association between genetic predisposition of general and central adiposity and systolic blood pressure (SBP) across body mass index (BMI) categories. Additionally, we explored whether, among females, the metabolic factors, triglyceride-to-HDL cholesterol (TG/HDL-C) ratio, glycated hemoglobin (HbA1c), and serum uric acid (SUA), modulate these relationships.

49,188 Taiwanese ancestry females

Chapter III

Study Statistics

Key metrics and study information

49188
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Taiwan
Recruitment Country
Chapter IV

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