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Research Publication

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier

Esha Bandyopadhyay, David Witonsky, Constanza de la Fuente Castro et al.

41160688 PubMed ID
32 Authors
2025-10-31 Published
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

EB
Esha Bandyopadhyay
DW
David Witonsky
CD
Constanza de la Fuente Castro
NP
Nagarjuna Pasupuleti
JA
Jose A. Urban Aragon
JL
Juhyeon Lee
VS
Vivaswat Shastry
NS
Nathan Sander
BA
Bhavna Ahlawat
AD
Aparna Dwivedi
TA
Tanzin Angmo
AS
Aman Sharma
AK
Amit Kaushik
HM
Hannah Marie Moots
JV
J. Víctor Moreno-Mayar
SK
Sachin Kumar
RC
Rakesh Chandra Bhatt
KB
Kavita Bist Mengwal
HC
Hari Chauhan
RK
Rajinder K. Ganjoo
VM
Veena Mushrif-Tripathy
SB
Simadri Bihari Ota
CW
Christina Warinner
MA
Mark Aldenderfer
AD
Anna Di Rienzo
CJ
Choongwon Jeong
NS
Nagendra Singh Rawat
TN
Tsering Norbu
ES
Ekta Singh
VN
Vinod Nautiyal
MR
Maanasa Raghavan
NR
Niraj Rai
Chapter II

Abstract

Summary of the research findings

The authors report genome-wide analyses of ancient and present-day individuals from the northern Indian Himalayas and one older Central Himalayan (Nepal) specimen. Using data from seven ancient individuals (~2300–100 years BP), ten contemporary genomes from Himachal Pradesh, and one ~3370-year-old Nepal individual, they show that northern Himalayan populations are largely characterized by Tibetan-related ancestry with high-altitude adaptive variants, and that substantial Steppe-related ancestry is present in individuals dating from ~1300 years ago to the present. Some present-day individuals also show lowland South Asian admixture. The results indicate temporally dynamic admixture events alongside genetic continuity at the northern Himalayan frontier.

Chapter III

Analysis

Comprehensive review of ancestry and genetic findings

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Summary

Key Findings

Ancestry Insights

Traits Analysis

Historical Context

Scientific Assessment