Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier
Esha Bandyopadhyay, David Witonsky, Constanza de la Fuente Castro et al.
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Abstract
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The authors report genome-wide analyses of ancient and present-day individuals from the northern Indian Himalayas and one older Central Himalayan (Nepal) specimen. Using data from seven ancient individuals (~2300–100 years BP), ten contemporary genomes from Himachal Pradesh, and one ~3370-year-old Nepal individual, they show that northern Himalayan populations are largely characterized by Tibetan-related ancestry with high-altitude adaptive variants, and that substantial Steppe-related ancestry is present in individuals dating from ~1300 years ago to the present. Some present-day individuals also show lowland South Asian admixture. The results indicate temporally dynamic admixture events alongside genetic continuity at the northern Himalayan frontier.
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