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Research Publication

Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry

Hajdinjak M, Mafessoni F, Skov L et al.

33828320 PubMed ID
32 Authors
2021 Apr Published
6 Samples
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HM
Hajdinjak M
MF
Mafessoni F
SL
Skov L
VB
Vernot B
HA
Hübner A
FQ
Fu Q
EE
Essel E
NS
Nagel S
NB
Nickel B
RJ
Richter J
MO
Moldovan OT
CS
Constantin S
EE
Endarova E
ZN
Zahariev N
SR
Spasov R
WF
Welker F
SG
Smith GM
SV
Sinet-Mathiot V
PL
Paskulin L
FH
Fewlass H
TS
Talamo S
RZ
Rezek Z
SS
Sirakova S
SN
Sirakov N
MS
McPherron SP
TT
Tsanova T
HJ
Hublin JJ
PB
Peter BM
MM
Meyer M
SP
Skoglund P
KJ
Kelso J
PS
Pääbo S
Chapter II

Abstract

Summary of the research findings

Modern humans appeared in Europe by at least 45,000 years ago1-5, but the extent of their interactions with Neanderthals, who disappeared by about 40,000 years ago6, and their relationship to the broader expansion of modern humans outside Africa are poorly understood. Here we present genome-wide data from three individuals dated to between 45,930 and 42,580 years ago from Bacho Kiro Cave, Bulgaria1,2. They are the earliest Late Pleistocene modern humans known to have been recovered in Europe so far, and were found in association with an Initial Upper Palaeolithic artefact assemblage. Unlike two previously studied individuals of similar ages from Romania7 and Siberia8 who did not contribute detectably to later populations, these individuals are more closely related to present-day and ancient populations in East Asia and the Americas than to later west Eurasian populations. This indicates that they belonged to a modern human migration into Europe that was not previously known from the genetic record, and provides evidence that there was at least some continuity between the earliest modern humans in Europe and later people in Eurasia. Moreover, we find that all three individuals had Neanderthal ancestors a few generations back in their family history, confirming that the first European modern humans mixed with Neanderthals and suggesting that such mixing could have been common.

Chapter III

Ancient DNA Samples

6 ancient DNA samples referenced in this publication

6 Samples
Sample ID Date/Era Country Locality Sex mtDNA Y-DNA
F6-620 41976 BCE Bulgaria Balkan Mountains. Bacho Kiro Cave M
AA7-738 41976 BCE Bulgaria Balkan Mountains. Bacho Kiro Cave M
BB7-240 44169 BCE Bulgaria Balkan Mountains. Bacho Kiro Cave M
CC7-2289 42446 BCE Bulgaria Balkan Mountains. Bacho Kiro Cave F
CC7-335 43975 BCE Bulgaria Balkan Mountains. Bacho Kiro Cave M
BK-1653 33333 BCE Bulgaria Balkan Mountains. Bacho Kiro Cave F
Chapter IV

Analysis

Comprehensive review of ancestry and genetic findings

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Summary

Key Findings

Ancestry Insights

Traits Analysis

Historical Context

Scientific Assessment