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GWAS Study

A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.

Kim HC, Lee JY, Sung H et al.

22452962 PubMed ID
GWAS Study Type
12219 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KH
Kim HC
LJ
Lee JY
SH
Sung H
CJ
Choi JY
PS
Park SK
LK
Lee KM
KY
Kim YJ
GM
Go MJ
LL
Li L
CY
Cho YS
PM
Park M
KD
Kim DJ
OJ
Oh JH
KJ
Kim JW
JJ
Jeon JP
JS
Jeon SY
MH
Min H
KH
Kim HM
PJ
Park J
YK
Yoo KY
ND
Noh DY
AS
Ahn SH
LM
Lee MH
KS
Kim SW
LJ
Lee JW
PB
Park BW
PW
Park WY
KE
Kim EH
KM
Kim MK
HW
Han W
LS
Lee SA
MK
Matsuo K
SC
Shen CY
WP
Wu PE
HC
Hsiung CN
LJ
Lee JY
KH
Kim HL
HB
Han BG
KD
Kang D
Chapter II

Abstract

Summary of the research findings

Introduction: Although approximately 25 common genetic susceptibility loci have been identified to be independently associated with breast cancer risk through genome-wide association studies (GWAS), the genetic risk variants reported to date only explain a small fraction of the heritability of breast cancer. Furthermore, GWAS-identified loci were primarily identified in women of European descent.

2,273 Korean ancestry cases, 2,052 Korean ancestry controls

Chapter III

Study Statistics

Key metrics and study information

12219
Total Participants
GWAS
Study Type
Yes
Replicated
4,049 Korean ancestry cases, 3,845 Korean ancestry controls
Replication Participants
East Asian
Ancestry
Republic of Korea
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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