The largest genome-wide association study for breast cancer in Taiwanese Han population.
Hsu YC, Chen HL, Cheng CF et al.
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Abstract
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Purpose: Breast cancer is a molecularly heterogeneous disease, and multiple genetic variants contribute to its development and prognosis. Most of previous genome-wide association studies (GWASs) and polygenic risk scores (PRSs) analyses focused on studying breast cancers of Caucasian populations, which may not be applicable to other population. Therefore, we conducted the largest breast cancer cohort of Taiwanese population to fill in the knowledge gap.
2,496 Taiwanese Han ancestry cases, 9,984 Taiwanese Han ancestry controls
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