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The ATXN2-SH2B3 locus is associated with peripheral arterial disease: an electronic medical record-based genome-wide association study.

Kullo IJ, Shameer K, Jouni H et al.

25009551 PubMed ID
GWAS Study Type
5036 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KI
Kullo IJ
SK
Shameer K
JH
Jouni H
LT
Lesnick TG
PJ
Pathak J
CC
Chute CG
DA
de Andrade M
Chapter II

Abstract

Summary of the research findings

Objectives: In contrast to coronary heart disease (CHD), genetic variants that influence susceptibility to peripheral arterial disease (PAD) remain largely unknown.

1,641 European ancestry cases, 1,604 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

5036
Total Participants
GWAS
Study Type
Yes
Replicated
740 European ancestry cases, 1,501 European ancestry controls
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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