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GWAS Study

Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos.

Pino-Yanes M, Gignoux CR, Galanter JM et al.

25488688 PubMed ID
GWAS Study Type
3788 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PM
Pino-Yanes M
GC
Gignoux CR
GJ
Galanter JM
LA
Levin AM
CC
Campbell CD
EC
Eng C
HS
Huntsman S
NK
Nishimura KK
GP
Gourraud PA
MK
Mohajeri K
OB
O'Roak BJ
HD
Hu D
MR
Mathias RA
NE
Nguyen EA
RL
Roth LA
PB
Padhukasahasram B
MA
Moreno-Estrada A
SK
Sandoval K
WC
Winkler CA
LF
Lurmann F
DA
Davis A
FH
Farber HJ
MK
Meade K
AP
Avila PC
SD
Serebrisky D
CR
Chapela R
FJ
Ford JG
LM
Lenoir MA
TS
Thyne SM
BE
Brigino-Buenaventura E
BL
Borrell LN
RW
Rodriguez-Cintron W
SS
Sen S
KR
Kumar R
RJ
Rodriguez-Santana JR
BC
Bustamante CD
MF
Martinez FD
RB
Raby BA
WS
Weiss ST
ND
Nicolae DL
OC
Ober C
MD
Meyers DA
BE
Bleecker ER
MS
Mack SJ
HR
Hernandez RD
EE
Eichler EE
BK
Barnes KC
WL
Williams LK
TD
Torgerson DG
BE
Burchard EG
Chapter II

Abstract

Summary of the research findings

IgE is a key mediator of allergic inflammation, and its levels are frequently increased in patients with allergic disorders.

1,854 Hispanic asthmatic individuals, 1,480 Hispanic individuals

Chapter III

Study Statistics

Key metrics and study information

3788
Total Participants
GWAS
Study Type
Yes
Replicated
454 Hispanic asthmatic individuals
Replication Participants
Hispanic or Latin American
Ancestry
Puerto Rico, U.S., Mexico
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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