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GWAS Study

A genome wide association study of fast beta EEG in families of European ancestry.

Meyers JL, Zhang J, Manz N et al.

28040410 PubMed ID
GWAS Study Type
1564 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MJ
Meyers JL
ZJ
Zhang J
MN
Manz N
RM
Rangaswamy M
KC
Kamarajan C
WL
Wetherill L
CD
Chorlian DB
KS
Kang SJ
BL
Bauer L
HV
Hesselbrock V
KJ
Kramer J
KS
Kuperman S
NJ
Nurnberger JI
TJ
Tischfield J
WJ
Wang JC
EH
Edenberg HJ
GA
Goate A
FT
Foroud T
PB
Porjesz B
Chapter II

Abstract

Summary of the research findings

Differences in fast beta (20-28Hz) electroencephalogram (EEG) oscillatory activity distinguish some individuals with psychiatric and substance use disorders, suggesting that it may be a useful endophenotype for studying the genetics of disorders characterized by neural hyper-excitability. Despite the high heritability estimates provided by twin and family studies, there have been relatively few genetic studies of beta EEG, and to date only one genetic association finding has replicated (i.e., GABRA2).

1,564 European ancestry individuals from 117 alcohol dependence affected families

Chapter III

Study Statistics

Key metrics and study information

1564
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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