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GWAS Study

A Genome-Wide Association Study of Vertical Cup-Disc Ratio in a Latino Population.

Nannini DR, Torres M, Chen YI et al.

28061514 PubMed ID
GWAS Study Type
4537 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ND
Nannini DR
TM
Torres M
CY
Chen YI
TK
Taylor KD
RJ
Rotter JI
VR
Varma R
GX
Gao X
Chapter II

Abstract

Summary of the research findings

Purpose: Vertical cup-disc ratio (VCDR) is used as a clinical assessment measure to identify and monitor glaucomatous damage to the optic nerve. Previous genetic studies conducted in European and Asian populations have identified many loci associated with VCDR. The genetic factors in other ethnic populations, such as Latino, influencing VCDR remain to be determined. Here, we describe the first genome-wide association study (GWAS) on VCDR in Latino individuals.

3,596 Latino individuals

Chapter III

Study Statistics

Key metrics and study information

4537
Total Participants
GWAS
Study Type
Yes
Replicated
941 Latino individuals
Replication Participants
Hispanic or Latin American
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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