Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity.
Hu H, Li H, Li J et al.
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Abstract
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The activity of cerebrospinal fluid (CSF) β-site APP cleaving enzyme (BACE) is a potential diagnostic biomarker for Alzheimer disease (AD).
86 European ancestry Alzheimer's disease cases, 163 European ancestry mild cognitive impairment cases, 91 European ancestry controls
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