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GWAS Study

17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage.

Marini S, Devan WJ, Radmanesh F et al.

29915124 PubMed ID
GWAS Study Type
299 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MS
Marini S
DW
Devan WJ
RF
Radmanesh F
ML
Miyares L
PT
Poterba T
HB
Hansen BM
NB
Norrving B
JJ
Jimenez-Conde J
GE
Giralt-Steinhauer E
ER
Elosua R
CE
Cuadrado-Godia E
SC
Soriano C
RJ
Roquer J
KC
Kourkoulis CE
AA
Ayres AM
SK
Schwab K
TD
Tirschwell DL
SM
Selim M
BD
Brown DL
SS
Silliman SL
WB
Worrall BB
MJ
Meschia JF
KC
Kidwell CS
MJ
Montaner J
FI
Fernandez-Cadenas I
DP
Delgado P
GS
Greenberg SM
LA
Lindgren A
MC
Matouk C
SK
Sheth KN
WD
Woo D
AC
Anderson CD
RJ
Rosand J
FG
Falcone GJ
Chapter II

Abstract

Summary of the research findings

Background and purpose: Hematoma volume is an important determinant of clinical outcome in spontaneous intracerebral hemorrhage (ICH). We performed a genome-wide association study (GWAS) of hematoma volume with the aim of identifying novel biological pathways involved in the pathophysiology of primary brain injury in ICH.

228 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

299
Total Participants
GWAS
Study Type
Yes
Replicated
71 European ancestry cases
Replication Participants
European
Ancestry
Sweden, Spain, U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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