Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.
Hauser MA, Allingham RR, Aung T et al.
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Abstract
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Importance: Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations of African ancestry compared with European or Asian ancestry. Despite this, individuals of African ancestry remain understudied in genomic research for blinding disorders.
694 African American cases, 1,590 Sub-Saharan African cases, 596 African American controls, 1,485 Sub-Saharan African controls
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