A Genome-Wide Association Study in Early COPD: Identification of One Major Susceptibility Loci.
Lee YJ, Choi S, Kwon SY et al.
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Identifying the genetic basis of airflow limitation is one of the most interesting issues for understanding chronic obstructive pulmonary disease (COPD) pathophysiology. Several studies have shown that some genetic variants associated with COPD have been identified in genome-wide association study (GWAS), especially in patients with moderate to severe COPD; genetic susceptibility for airflow limitation in the early COPD phase has not been widely studied.
38 Korean ancestry cases, 1,778 Korean ancestry controls
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