Susceptibility loci and polygenic architecture highlight population specific and common genetic features in inguinal hernias: genetics in inguinal hernias.
Hikino K, Koido M, Tomizuka K et al.
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Abstract
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The underlying pathology of inguinal hernia is still not fully known; thus, further investigations of genetic backgrounds is needed. Here, we aimed to identify genetic factors attributing to inguinal hernias and explore the polygenic architecture of which some components are population-specific, while others are more common among populations.
1,983 Japanese ancestry cases, 172,507 Japanese ancestry controls
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