Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3.
Nolan J, Campbell PJ, Brown SJ et al.
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Abstract
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Objective: Genetic factors underpin the narrow intraindividual variability of thyroid function, although precise contributions of environmental vs genetic factors remain uncertain. We sought to clarify the heritability of thyroid function traits and thyroid peroxidase antibody (TPOAb) positivity and identify single nucleotide polymorphisms (SNPs) contributing to the trait variance.
2,832 European ancestry individuals
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