Genetic susceptibility to cognitive decline following craniospinal irradiation for pediatric central nervous system tumors.
Brown AL, Sok P, Raghubar KP et al.
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Abstract
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Survivors of pediatric central nervous system (CNS) tumors treated with craniospinal irradiation (CSI) exhibit long-term cognitive difficulties. Goals of this study were to evaluate longitudinal effects of candidate and novel genetic variants on cognitive decline following CSI.
150 European ancestry individuals
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