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Genome-wide association study reveals HSF2, GJA1 and TRIM36 as susceptibility genes for preeclampsia: a community-based population study in Tianjin, China.

Cao Z, Ma L, Cai W et al.

37735976 PubMed ID
GWAS Study Type
435 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CZ
Cao Z
ML
Ma L
CW
Cai W
NX
Niu X
YN
Yang N
NJ
Ni J
WX
Wang X
WM
Wei M
CS
Chen S
LY
Li Y
Chapter II

Abstract

Summary of the research findings

Preeclampsia (PE) mainly occurs in pregnant women and is hereditary. Several genome-wide association studies (GWAS) on Caucasian samples have reported some gene loci that are associated with preeclampsia. However, these studies have not reached consistent conclusions. No previous GWAS has examined preeclampsia in the Chinese Han population.

92 Han Chinese ancestry cases, 187 Han Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

435
Total Participants
GWAS
Study Type
Yes
Replicated
52 Han Chinese ancestry cases, 104 Han Chinese ancestry controls
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

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