A unified genealogy of modern and ancient genomes
Wohns AW, Wong Y, Jeffery B et al.
Publication Details
Comprehensive information about this research publication
Abstract
Summary of the research findings
The sequencing of modern and ancient genomes from around the world has revolutionized our understanding of human history and evolution. However, the problem of how best to characterize ancestral relationships from the totality of human genomic variation remains unsolved. Here, we address this challenge with nonparametric methods that enable us to infer a unified genealogy of modern and ancient humans. This compact representation of multiple datasets explores the challenges of missing and erroneous data and uses ancient samples to constrain and date relationships. We demonstrate the power of the method to recover relationships between individuals and populations as well as to identify descendants of ancient samples. Finally, we introduce a simple nonparametric estimator of the geographical location of ancestors that recapitulates key events in human history.
Ancient DNA Samples
8 ancient DNA samples referenced in this publication
| Sample ID | Date/Era | Country | Locality | Sex | mtDNA | Y-DNA |
|---|---|---|---|---|---|---|
| I3388 | 2800 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | F | U5a1d2b* |
|
| I3949 | 2844 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | M | U5a1d2b* |
Q-FT380500 |
| I3950 | 2879 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | M | U5b2a1a-a* |
Q-FT380500 |
| I6714 | 2618 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | M | U5a1d2b* |
Q-FT380500 |
| I6714 | 2618 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | M | U5a1d2b* |
Q-FT380500 |
| I3949 | 2844 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | M | U5a1d2b* |
Q-FT380500 |
| I3950 | 2879 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | M | U5b2a1a-a* |
Q-FT380500 |
| I3388 | 2800 BCE | Russia | Altai Mountains. Yenisey River. left bank of Karasuk tributary. Karasuk III | F | U5a1d2b* |
|
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