aHISplex: an imputation based method for eye, hair and skin colour prediction from low coverage ancient DNA
C. A. Phillips, E. Altınışık, S. Park et al.
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Abstract
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We describe aHISplex, a new method for imputing phenotypes from ancient DNA based on a modern reference panel. We show that it performs well for eye, hair, and skin color prediction even with low coverage data (>0.05X) typical of many ancient DNA samples. We demonstrate its utility on published ancient DNA data, showing good concordance with previously reported phenotypes.
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