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GWAS Study

Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.

Paterson AD, Lopes-Virella MF, Waggott D et al.

19729612 PubMed ID
GWAS Study Type
1162 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PA
Paterson AD
LM
Lopes-Virella MF
WD
Waggott D
BA
Boright AP
HS
Hosseini SM
CR
Carter RE
SE
Shen E
ML
Mirea L
BB
Bharaj B
SL
Sun L
BS
Bull SB
Chapter II

Abstract

Summary of the research findings

Elevated serum soluble E-selectin levels have been associated with a number of diseases. Although E-selectin levels are heritable, little is known about the specific genetic factors involved. E-selectin levels have been associated with the ABO blood group phenotype.

685 European ancestry individuals with type 1 diabetes

Chapter III

Study Statistics

Key metrics and study information

1162
Total Participants
GWAS
Study Type
Yes
Replicated
477 European ancestry individuals
Replication Participants
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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