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GWAS Study

Genomewide association study of leprosy.

Zhang FR, Huang W, Chen SM et al.

20018961 PubMed ID
GWAS Study Type
11140 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ZF
Zhang FR
HW
Huang W
CS
Chen SM
SL
Sun LD
LH
Liu H
LY
Li Y
CY
Cui Y
YX
Yan XX
YH
Yang HT
YR
Yang RD
CT
Chu TS
ZC
Zhang C
ZL
Zhang L
HJ
Han JW
YG
Yu GQ
QC
Quan C
YY
Yu YX
ZZ
Zhang Z
SB
Shi BQ
ZL
Zhang LH
CH
Cheng H
WC
Wang CY
LY
Lin Y
ZH
Zheng HF
FX
Fu XA
ZX
Zuo XB
WQ
Wang Q
LH
Long H
SY
Sun YP
CY
Cheng YL
TH
Tian HQ
ZF
Zhou FS
LH
Liu HX
LW
Lu WS
HS
He SM
DW
Du WL
SM
Shen M
JQ
Jin QY
WY
Wang Y
LH
Low HQ
ET
Erwin T
YN
Yang NH
LJ
Li JY
ZX
Zhao X
JY
Jiao YL
ML
Mao LG
YG
Yin G
JZ
Jiang ZX
WX
Wang XD
YJ
Yu JP
HZ
Hu ZH
GC
Gong CH
LY
Liu YQ
LR
Liu RY
WD
Wang DM
WD
Wei D
LJ
Liu JX
CW
Cao WK
CH
Cao HZ
LY
Li YP
YW
Yan WG
WS
Wei SY
WK
Wang KJ
HM
Hibberd ML
YS
Yang S
ZX
Zhang XJ
LJ
Liu JJ
Chapter II

Abstract

Summary of the research findings

The narrow host range of Mycobacterium leprae and the fact that it is refractory to growth in culture has limited research on and the biologic understanding of leprosy. Host genetic factors are thought to influence susceptibility to infection as well as disease progression.

706 Han Chinese ancestry cases, 1,225 Han Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

11140
Total Participants
GWAS
Study Type
Yes
Replicated
3,254 Chinese ancestry cases, 5,955 Chinese ancestry controls
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.