Genome-wide association of lipid-lowering response to statins in combined study populations.
Barber MJ, Mangravite LM, Hyde CL et al.
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Abstract
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Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three trials of statin efficacy.
3,928 European ancestry individuals
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