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Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.

Koriyama H, Nakagami H, Katsuya T et al.

20610895 PubMed ID
GWAS Study Type
3792 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KH
Koriyama H
NH
Nakagami H
KT
Katsuya T
SK
Sugimoto K
YH
Yamashita H
TY
Takami Y
MS
Maeda S
KM
Kubo M
TA
Takahashi A
NY
Nakamura Y
OT
Ogihara T
RH
Rakugi H
KY
Kaneda Y
MR
Morishita R
Chapter II

Abstract

Summary of the research findings

Aim: Peripheral arterial disease (PAD) is a common cause of cardiovascular morbidity and an independent predictor of cardiovascular mortality. However, little is known about the genetic basis of PAD. To elucidate this, we performed a two-staged genome-wide association study in Japanese individuals.

195 Japanese ancestry cases, 1,358 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3792
Total Participants
GWAS
Study Type
Yes
Replicated
699 Japanese ancestry cases, 1,540 Japanese ancestry controls
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

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