Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.
Kong X, Cho MH, Anderson W et al.
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Abstract
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Rationale: chronic obstructive pulmonary disease (COPD), characterized by airflow limitation, is a disorder with high phenotypic and genetic heterogeneity. Pulmonary emphysema is a major but variable component of COPD; familial data suggest that different components of COPD, such as emphysema, may be influenced by specific genetic factors.
2,383 European ancestry cases
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