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GWAS Study

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

Reilly MP, Li M, He J et al.

21239051 PubMed ID
GWAS Study Type
19776 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RM
Reilly MP
LM
Li M
HJ
He J
FJ
Ferguson JF
SI
Stylianou IM
MN
Mehta NN
BM
Burnett MS
DJ
Devaney JM
KC
Knouff CW
TJ
Thompson JR
HB
Horne BD
SA
Stewart AF
AT
Assimes TL
WP
Wild PS
AH
Allayee H
NP
Nitschke PL
PR
Patel RS
MN
Martinelli N
GD
Girelli D
QA
Quyyumi AA
AJ
Anderson JL
EJ
Erdmann J
HA
Hall AS
SH
Schunkert H
QT
Quertermous T
BS
Blankenberg S
HS
Hazen SL
RR
Roberts R
KS
Kathiresan S
SN
Samani NJ
ES
Epstein SE
RD
Rader DJ
Chapter II

Abstract

Summary of the research findings

We tested whether genetic factors distinctly contribute to either development of coronary atherosclerosis or, specifically, to myocardial infarction in existing coronary atherosclerosis.

1,808 European ancestry cases, 915 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

19776
Total Participants
GWAS
Study Type
Yes
Replicated
10,585 European ancestry cases, 6,468 European ancestry controls
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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