A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor.
Byrne EM, Johnson J, McRae AF et al.
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Abstract
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Objectives: To identify common genetic variants that predispose to caffeine-induced insomnia and to test whether genes whose expression changes in the presence of caffeine are enriched for association with caffeine-induced insomnia.
2,402 European ancestry individuals from 1,470 families
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