Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Betcheva ET, Yosifova AG, Mushiroda T et al.
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Abstract
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Objective: Schizophrenia, the most common major psychiatric disorder (or group of disorders), entails severe decline of higher functions, principally with alterations in cognitive functioning and reality perception. Both genetic and environmental factors are involved in its pathogenesis; however, its genetic background still needs to be clarified. The objective of the study was to reveal genetic markers associated with schizophrenia in the Bulgarian population.
188 European ancestry cases, 376 European ancestry controls
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