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GWAS Study

Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.

Jin G, Zheng SL, Lilja H et al.

23359319 PubMed ID
GWAS Study Type
4914 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JG
Jin G
ZS
Zheng SL
LH
Lilja H
KS
Kim ST
TS
Tao S
GZ
Gao Z
YT
Young T
WF
Wiklund F
FJ
Feng J
IW
Isaacs WB
RR
Rittmaster RS
GH
Gronberg H
CL
Condreay LD
SJ
Sun J
XJ
Xu J
Chapter II

Abstract

Summary of the research findings

Percentage of free-to-total prostate-specific antigen (%fPSA) is an independent predictor of risk for prostate cancer among men with modestly elevated level of total PSA (tPSA) in blood. Physiological and pathological factors have been shown to influence the %fPSA value and diagnostic accuracy.

3,192 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

4914
Total Participants
GWAS
Study Type
Yes
Replicated
1,722 European ancestry individuals
Replication Participants
European
Ancestry
Sweden
Recruitment Country
Chapter IV

AI-Generated Summary

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