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Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study.

Manichaikul A, Hoffman EA, Smolonska J et al.

24383474 PubMed ID
GWAS Study Type
13937 Participants
217 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MA
Manichaikul A
HE
Hoffman EA
SJ
Smolonska J
GW
Gao W
CM
Cho MH
BH
Baumhauer H
BM
Budoff M
AJ
Austin JH
WG
Washko GR
CJ
Carr JJ
KJ
Kaufman JD
PT
Pottinger T
PC
Powell CA
WC
Wijmenga C
ZP
Zanen P
GH
Groen HJ
PD
Postma DS
WA
Wanner A
RF
Rouhani FN
BM
Brantly ML
PR
Powell R
SB
Smith BM
RD
Rabinowitz D
RL
Raffel LJ
HS
Hinckley Stukovsky KD
CJ
Crapo JD
BT
Beaty TH
HJ
Hokanson JE
SE
Silverman EK
DJ
Dupuis J
OG
O'Connor GT
BH
Boezen HM
RS
Rich SS
BR
Barr RG
Chapter II

Abstract

Summary of the research findings

Rationale: Pulmonary emphysema overlaps partially with spirometrically defined chronic obstructive pulmonary disease and is heritable, with moderately high familial clustering.

2,587 European ancestry individuals, 2,510 African American individuals, 2,113 Hispanic individuals, 704 Chinese ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

13937
Total Participants
GWAS
Study Type
Yes
Replicated
6,023 European ancestry individuals
Replication Participants
European, East Asian, African American or Afro-Caribbean, Hispanic or Latin American
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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