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GWAS Study

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

Tang W, Kowgier M, Loth DW et al.

24983941 PubMed ID
GWAS Study Type
32827 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TW
Tang W
KM
Kowgier M
LD
Loth DW
SA
Soler Artigas M
JB
Joubert BR
HE
Hodge E
GS
Gharib SA
SA
Smith AV
RI
Ruczinski I
GV
Gudnason V
MR
Mathias RA
HT
Harris TB
HN
Hansel NN
LL
Launer LJ
BK
Barnes KC
HJ
Hansen JG
AE
Albrecht E
AM
Aldrich MC
AM
Allerhand M
BR
Barr RG
BG
Brusselle GG
CD
Couper DJ
CI
Curjuric I
DG
Davies G
DI
Deary IJ
DJ
Dupuis J
FT
Fall T
FM
Foy M
FN
Franceschini N
GW
Gao W
GS
Gläser S
GX
Gu X
HD
Hancock DB
HJ
Heinrich J
HA
Hofman A
IM
Imboden M
IE
Ingelsson E
JA
James A
KS
Karrasch S
KB
Koch B
KS
Kritchevsky SB
KA
Kumar A
LL
Lahousse L
LG
Li G
LL
Lind L
LC
Lindgren C
LY
Liu Y
LK
Lohman K
LT
Lumley T
MW
McArdle WL
MB
Meibohm B
MA
Morris AP
MA
Morrison AC
MB
Musk B
NK
North KE
PL
Palmer LJ
PN
Probst-Hensch NM
PB
Psaty BM
RF
Rivadeneira F
RJ
Rotter JI
SH
Schulz H
SL
Smith LJ
SA
Sood A
SJ
Starr JM
SD
Strachan DP
TA
Teumer A
UA
Uitterlinden AG
VH
Völzke H
VA
Voorman A
WL
Wain LV
WM
Wells MT
WJ
Wilk JB
WO
Williams OD
HS
Heckbert SR
SB
Stricker BH
LS
London SJ
FM
Fornage M
TM
Tobin MD
OG
O'Connor GT
HI
Hall IP
CP
Cassano PA
Chapter II

Abstract

Summary of the research findings

Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.

up to 27,249 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

32827
Total Participants
GWAS
Study Type
Yes
Replicated
1,494 individuals, 4,084 mild chronic obstructive pulmonary disease smoker individuals
Replication Participants
European
Ancestry
Australia, Netherlands, Germany, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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