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Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.

Renauer PA, Saruhan-Direskeneli G, Coit P et al.

25604533 PubMed ID
GWAS Study Type
2090 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RP
Renauer PA
SG
Saruhan-Direskeneli G
CP
Coit P
AA
Adler A
AK
Aksu K
KG
Keser G
AF
Alibaz-Oner F
AS
Aydin SZ
KS
Kamali S
IM
Inanc M
CS
Carette S
CD
Cuthbertson D
HG
Hoffman GS
AS
Akar S
OF
Onen F
AN
Akkoc N
KN
Khalidi NA
KC
Koening C
KO
Karadag O
KS
Kiraz S
LC
Langford CA
MK
Maksimowicz-McKinnon K
MC
McAlear CA
OZ
Ozbalkan Z
AA
Ates A
KY
Karaaslan Y
DN
Duzgun N
MP
Monach PA
OH
Ozer HT
EE
Erken E
OM
Ozturk MA
YA
Yazici A
CA
Cefle A
OA
Onat AM
KB
Kisacik B
PC
Pagnoux C
KT
Kasifoglu T
SE
Seyahi E
FI
Fresko I
SP
Seo P
SA
Sreih AG
WK
Warrington KJ
YS
Ytterberg SR
CV
Cobankara V
CD
Cunninghame-Graham DS
VT
Vyse TJ
PO
Pamuk ON
TS
Tunc SE
DE
Dalkilic E
BM
Bicakcigil M
YS
Yentur SP
WJ
Wren JD
MP
Merkel PA
DH
Direskeneli H
SA
Sawalha AH
Chapter II

Abstract

Summary of the research findings

Objective: Takayasu arteritis is a rare large vessel vasculitis with incompletely understood etiology. This study was undertaken to perform the first unbiased genome-wide association analysis of Takayasu arteritis.

516 Turkish ancestry cases, 119 European ancestry cases, 462 Turkish ancestry controls, 993 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2090
Total Participants
GWAS
Study Type
No
Replicated
European, Other
Ancestry
U.S., Turkey
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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