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GWAS Study

Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).

Wojczynski MK, Parnell LD, Pollin TI et al.

26256467 PubMed ID
GWAS Study Type
1715 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WM
Wojczynski MK
PL
Parnell LD
PT
Pollin TI
LC
Lai CQ
FM
Feitosa MF
OJ
O'Connell JR
FA
Frazier-Wood AC
GQ
Gibson Q
AS
Aslibekyan S
RK
Ryan KA
PM
Province MA
TH
Tiwari HK
OJ
Ordovas JM
SA
Shuldiner AR
AD
Arnett DK
BI
Borecki IB
Chapter II

Abstract

Summary of the research findings

Objective: The triglyceride (TG) response to a high-fat meal (postprandial lipemia, PPL) affects cardiovascular disease risk and is influenced by genes and environment. Genes involved in lipid metabolism have dominated genetic studies of PPL TG response. We sought to elucidate common genetic variants through a genome-wide association (GWA) study in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).

872 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1715
Total Participants
GWAS
Study Type
Yes
Replicated
843 Old Order Amish individuals
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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