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GWAS Study

Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies.

Sekula P, Li Y, Stanescu HC et al.

27333618 PubMed ID
GWAS Study Type
1184 Participants
81 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SP
Sekula P
LY
Li Y
SH
Stanescu HC
WM
Wuttke M
EA
Ekici AB
BD
Bockenhauer D
WG
Walz G
PS
Powis SH
KJ
Kielstein JT
BP
Brenchley P
EK
Eckardt KU
KF
Kronenberg F
KR
Kleta R
KA
Köttgen A
Chapter II

Abstract

Summary of the research findings

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants identified MN-associated loci at HLA-DQA1 and PLA2R1.

323 European ancestry cases, 345 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1184
Total Participants
GWAS
Study Type
Yes
Replicated
137 European ancestry cases, 379 European ancestry controls
Replication Participants
European
Ancestry
Chapter IV

AI-Generated Summary

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