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GWAS Study

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.

Nakayama A, Nakaoka H, Yamamoto K et al.

27899376 PubMed ID
GWAS Study Type
8191 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NA
Nakayama A
NH
Nakaoka H
YK
Yamamoto K
SM
Sakiyama M
SA
Shaukat A
TY
Toyoda Y
OY
Okada Y
KY
Kamatani Y
NT
Nakamura T
TT
Takada T
IK
Inoue K
YT
Yasujima T
YH
Yuasa H
SY
Shirahama Y
NH
Nakashima H
SS
Shimizu S
HT
Higashino T
KY
Kawamura Y
OH
Ogata H
KM
Kawaguchi M
OY
Ohkawa Y
DI
Danjoh I
TA
Tokumasu A
OK
Ooyama K
IT
Ito T
KT
Kondo T
WK
Wakai K
SB
Stiburkova B
PK
Pavelka K
SL
Stamp LK
DN
Dalbeth N
SY
Sakurai Y
SH
Suzuki H
HM
Hosoyamada M
FS
Fujimori S
YT
Yokoo T
HT
Hosoya T
II
Inoue I
TA
Takahashi A
KM
Kubo M
OH
Ooyama H
ST
Shimizu T
IK
Ichida K
SN
Shinomiya N
MT
Merriman TR
MH
Matsuo H
Chapter II

Abstract

Summary of the research findings

Objective: A genome-wide association study (GWAS) of gout and its subtypes was performed to identify novel gout loci, including those that are subtype-specific.

945 Japanese ancestry cases, 1,213 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

8191
Total Participants
GWAS
Study Type
Yes
Replicated
1,396 Japanese ancestry cases, 1,268 Japanese ancestry controls, 1,319 European ancestry cases, 514 European ancestry controls, 971 Polynesian ancestry cases, 565 Polynesian ancestry controls
Replication Participants
European, Oceanian, East Asian
Ancestry
New Zealand, Japan
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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