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GWAS Study

A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants.

Bacchelli E, Cainazzo MM, Cameli C et al.

27957625 PubMed ID
GWAS Study Type
458 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BE
Bacchelli E
CM
Cainazzo MM
CC
Cameli C
GS
Guerzoni S
MA
Martinelli A
ZM
Zoli M
ME
Maestrini E
PL
Pini LA
Chapter II

Abstract

Summary of the research findings

Cluster Headache (CH) is a severe primary headache, with a poorly understood pathophysiology. Complex genetic factors are likely to play a role in CH etiology; however, no confirmed gene associations have been identified. The aim of this study is to identify genetic variants influencing risk to CH and to explore the potential pathogenic mechanisms.

99 Italian ancestry cases, 359 Italian ancestry smoker controls

Chapter III

Study Statistics

Key metrics and study information

458
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Italy
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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