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GWAS Study

A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients.

Paziewska A, Habior A, Rogowska A et al.

28056976 PubMed ID
GWAS Study Type
1377 Participants
104 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PA
Paziewska A
HA
Habior A
RA
Rogowska A
ZW
Zych W
GK
Goryca K
KJ
Karczmarski J
DM
Dabrowska M
AF
Ambrozkiewicz F
WB
Walewska-Zielecka B
KM
Krawczyk M
CH
Cichoz-Lach H
MP
Milkiewicz P
KA
Kowalik A
MK
Mucha K
RJ
Raczynska J
MJ
Musialik J
BG
Boryczka G
WM
Wasilewicz M
CI
Ciecko-Michalska I
FM
Ferenc M
JM
Janiak M
KA
Kanikowska A
SR
Stankiewicz R
HM
Hartleb M
MT
Mach T
GM
Grzymislawski M
RJ
Raszeja-Wyszomirska J
WE
Wunsch E
BT
Bobinski T
MM
Mikula M
OJ
Ostrowski J
Chapter II

Abstract

Summary of the research findings

Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are forms of hepatic autoimmunity, and risk for both diseases has a strong genetic component. This study aimed to define the genetic architecture of PBC and PSC within the Polish population.

443 Polish ancestry cases, 934 Polish ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1377
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Poland
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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