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GWAS Study

Genome-wide interaction study of dust mite allergen on lung function in children with asthma.

Forno E, Sordillo J, Brehm J et al.

28167095 PubMed ID
GWAS Study Type
1542 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FE
Forno E
SJ
Sordillo J
BJ
Brehm J
CW
Chen W
BT
Benos T
YQ
Yan Q
AL
Avila L
SM
Soto-Quirós M
CM
Cloutier MM
CA
Colón-Semidey A
AM
Alvarez M
AE
Acosta-Pérez E
WS
Weiss ST
LA
Litonjua AA
CG
Canino G
CJ
Celedón JC
Chapter II

Abstract

Summary of the research findings

Childhood asthma is likely the result of gene-by-environment (G × E) interactions. Dust mite is a known risk factor for asthma morbidity. Yet, there have been no genome-wide G × E studies of dust mite allergen on asthma-related phenotypes.

440 Puerto Rican ancestry child cases

Chapter III

Study Statistics

Key metrics and study information

1542
Total Participants
GWAS
Study Type
Yes
Replicated
497 European ancestry child cases, 605 Hispanic child cases
Replication Participants
European, Hispanic or Latin American
Ancestry
Puerto Rico, U.S., Costa Rica
Recruitment Country
Chapter IV

AI-Generated Summary

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