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GWAS Study

Genetic Determinants of Radiographic Knee Osteoarthritis in African Americans.

Liu Y, Yau MS, Yerges-Armstrong LM et al.

28916551 PubMed ID
GWAS Study Type
1217 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LY
Liu Y
YM
Yau MS
YL
Yerges-Armstrong LM
DD
Duggan DJ
RJ
Renner JB
HM
Hochberg MC
MB
Mitchell BD
JR
Jackson RD
JJ
Jordan JM
Chapter II

Abstract

Summary of the research findings

Objective: The etiology of knee osteoarthritis (OA), the most common form of arthritis, is complex and may differ by race or ethnicity. In recent years, genetic studies have identified many genetic variants associated with OA, but nearly all the studies were conducted in European whites and Asian Americans. Few studies have focused on the genetics of knee OA in African Americans.

742 African American cases, 475 African American controls

Chapter III

Study Statistics

Key metrics and study information

1217
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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