Exploring the genomic basis of early childhood caries: a pilot study.
Ballantine JL, Carlson JC, Ferreira Zandoná AG et al.
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Abstract
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Objective: A genetic component in early childhood caries (ECC) is theorized, but no genome-wide investigations of ECC have been conducted. This pilot study is part of a long-term research program aimed to: (1) determine the proportion of ECC variance attributable to the human genome and (2) identify ECC-associated genetic loci.
26 African American cases, 34 Hispanic cases, 13 European ancestry cases, 6 Native-American ancestry cases, 1 case, 41 African American controls, 40 Hispanic controls, 36 European ancestry controls, 15 Native-American ancestry controls.
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