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GWAS Study

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus.

Fan BJ, Chen X, Sondhi N et al.

29847655 PubMed ID
GWAS Study Type
12664 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FB
Fan BJ
CX
Chen X
SN
Sondhi N
SP
Sharmila PF
SN
Soumittra N
SS
Sripriya S
SS
Sacikala S
AR
Asokan R
FD
Friedman DS
PL
Pasquale LR
GX
Gao XR
VL
Vijaya L
CB
Cooke Bailey J
VV
Vitart V
MS
MacGregor S
HC
Hammond CJ
KC
Khor CC
HJ
Haines JL
GR
George R
WJ
Wiggs JL
Chapter II

Abstract

Summary of the research findings

Purpose: To identify genetic risk factors contributing to central corneal thickness (CCT) in individuals from South India, a population with a high prevalence of ocular disorders.

195 South Indian ancestry individuals from 15 families

Chapter III

Study Statistics

Key metrics and study information

12664
Total Participants
GWAS
Study Type
Yes
Replicated
1,520 Singaporean Indian individuals, 4,038 Mexican American individuals, 6,911 European ancestry individuals
Replication Participants
South Asian, European, Hispanic or Latin American
Ancestry
India, Singapore, U.K., Croatia, U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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